July 2023 · 14 bookmarks
Take a look at Françoise Barré-Sinoussi's lab notes from 1983 – the year she and Luc Montaigner discovered the Human Immunodeficiency Virus (HIV), the virus that causes AIDS.
In 1985, the first commercial blood test to detect HIV became available.
"Unsupervised" is an AI-driven art installation by artist Refik Anadol at MoMA. It uses Generative Adversarial Networks GANs to transform MoMA's collection of art, design, and photography into vibrant, 3-D animations displayed on a 24-foot-high LED wall
I see a of people using ChatGPT to generate recipes. Amateurs.
"Code Interpreter, here are academic papers on food flavor combinations and a database of 1,200 recipes, Do analyses & generate the ultimate unique recipe."
Spiced Espresso Poached Pears with Cocoa-Almond Sauce👇
A lab handbook can help with the day-to-day challenges of running a lab and promote a positive culture. Here are in-depth resources, including a template, to help you write your own:
Most business experiments do nothing, so many small radical experiments are better than a few big precise ones as they let you quickly screen for possible huge outcomes.
Here are the results of many A/B tests at Bing, the top 2% of ideas were responsible for 75% of the gains. 1/
The biggest signal that someone will iterate quickly in the future is that they iterated quickly in the past.
Building and shipping things quickly when you are young is great practice. It teaches you that making things and giving them to people is fun!
A CEO problem: blurry vision bias.
People aren’t motivated by abstract concepts (“the future of everything”), they are inspired by vivid images of the future. This paper suggests "mental time travel" - painting a picture of what the world looks like when you achieve your goal.
I have created 50 apps:
10% have failed
46% have not been monetized (yet)
44% have generated revenue
And I've had 8 apps acquired
My journey started on January 13, 2020 to cope with my mental breakdown:
«Fun to imagine» is a 1983 BBC TV series originally shot on 16mm film at Richard Feynman's house in Altadena, California. He explains that trees actually come from the air and why the heat from a fire is in fact the heat of the Sun:
Regularly talking to your users has the highest ROI of anything you can do.
“Worms dont know that humans who pass by are intelligent, so no reason to think humans would know if alien super-race did same”
A mind-blowing paper has come out today in @Nature
In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (science.org/doi/10.1126/sc…).
Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome.
The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution.
Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell.
When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part.
The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival.
The conclusion of the paper is metaphorically a quote from the Jurassic Park movie:
“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (
“Student: Dr. Einstein, Aren't these the same questions as last year's [physics] final exam?
Dr. Einstein: Yes; But this year the answers are different.”
― Albert Einstein
calling your product "Something AI" is like saying your product uses electricity — it's a commodity not a differentiator
instead explain what it does for me